The underlying mechanism is well known: put simply, synaptic signal transmission is triggered when calcium ions in the sender neuron bind to specific sensor proteins, which causes messengers—known as ...

Transcriptomic analyses revealed thousands of differentially expressed genes in the brain, with synaptogenesis signaling emerging as the most significantly disrupted pathway—even at the lowest ...

In mouse brain cells, and in follow-up work involving worms and human cortical neurons, the team found that many axons ...

Functional gastrointestinal disorders (FGIDs), including irritable bowel syndrome, functional dyspepsia, and chronic visceral pain syndromes, affect a ...

Researchers at VIB-KU Leuven shed light on an unusual signaling pathway that orchestrates synaptic structure and function during brain development. Leuven, 20 May 2025 - Researchers from the lab led ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Low-dose ephedrine disrupts synaptic signaling and behavior in adult zebrafish. Schematic overview of the experimental design, key neurotoxic mechanisms, and functional outcomes following chronic ...