Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital and Baylor College of Medicine recently made an important advance in neurodegenerative disease ...
“Taken together, our findings highlight both brain region-specific vulnerabilities and global molecular perturbations associated with alpha-synuclein biology and provide insights into early ...
Multiple system atrophy (MSA) is an adult-onset, rapidly progressive neurodegenerative disorder characterised by the aggregation of α-synuclein in oligodendroglial cytoplasmatic inclusions.1 ...
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the accumulation of misfolded ...
People with Parkinson’s disease have α-synuclein clumps in the brain, but these aggregates are not the only thing clogging them up. Constipation plagues many PD patients, often decades before motor ...