Nature

T Cell and B Cell Interactions in Autoimmunity and Immune Response

Understanding the interplay between T cells and B cells is pivotal to delineating both protective immunity and the pathogenesis of autoimmune diseases. Central to this dynamic are specialised CD4⁺ T ...
News Medical

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...
Fred Hutch

‘Getting the T’ on T cell populations in colorectal cancer

Colorectal cancer can be treated using immunotherapy approaches that use the immune cells to target cancer cells and induce the killing of those cancer cells. Some colorectal cancer types have been ...
GEN

Immune Cell Profiling in Type 1 Diabetes Identifies Changes in Memory T Cells and B Cells

Scientists analyzing human and mouse pancreatic lymph nodes (PLNs) and spleens have identified a distinct subset of CD4 memory helper T cells associated with type 1 diabetes (T1D). Reported by ...
ascopubs.org

Comparative analysis of T-cell subsets and vessel features in matched primary colorectal tumors and corresponding resected liver metastases.

Comprehensive clinicogenomic profiling of signet ring cell carcinoma across multiple organ sites. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a ...