T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

A cluster of recent studies has sharpened the scientific picture of how T cells switch on, tracking the molecular signals ...

New research links atopic dermatitis to S1P signalling pathways driving inflammation. Learn how this could shape future ...

The team shows that transient low-dose bortezomib treatment during CAR-T cell manufacturing dampens proteasome-driven heme ...

Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a ...

A technique that transforms immune cells into cancer-seeking bloodhounds may overcome a roadblock that has hampered immunotherapy for solid tumors, according to a new study by Stanford Medicine ...

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...

Lymph nodes are key control centers in the immune system and play an important role in defending the body against infections ...