Otsuka Pharmaceutical has shared more detailed data behind its kidney disease drug’s phase 3 win, showing the monoclonal antibody halved patients’ urine protein-to-creatinine ratio (UPCR) levels.
A urine protein-creatinine ratio (UPCR) test looks for high levels of protein in your urine, which can happen in kidney disease. Results that are higher than average may be a sign of a kidney-related ...
The trial met its primary endpoint showing a statistically significant reduction in 24-hour uPCR with sibeprenlimab vs placebo in patients with IgA nephropathy. Topline interim results were announced ...
An investigative treatment targeting APOL1 activity significantly improved proteinuria APOL1-mediated kidney disease (AMKD), a proof-of-concept phase IIa study found. In a single-arm, open-label study ...
Findings from the APPEAR-C3G trial showed a 35% reduction in 24-hour UPCR from baseline (primary endpoint) in the iptacopan group compared with the placebo group. The Food and Drug Administration (FDA ...
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Baseline renal parameters may useful in predicting the risk for preeclampsia among pregnant women, according to a study published online June 6 in Obstetrics & Gynecology. "[O]ur findings suggest that ...
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