A case study reviews the reformulation and scale up of high drug load prototype using wet granulation process for a model formulation. The reformulation of a 100-mg tablet into a 300-mgtablet ...

We try to use previous experience to develop the optimal granulation process for each new ingredient, but we sometimes get it wrong. Many times, we?ve taken materials from the granulator only to find ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

Pharmaceutical research and development (R&D) and industry require a continuous fluid-bed dryer that provides a lengthy process time and delivers a high standard for a long time. This article ...

Granulation is a key step in solid dosage manufacturing and directly impacts product quality and process stability. However, the choice of wet granulation method is often driven by legacy decisions ...

Granulation processes are used for converting light fine powders into large, dense granules to make fast-dissolving drinks, optimized blends for compression tableting, and granules for waste water ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...