Triptolide (1) is a structurally unique diterpene triepoxide isolated from a traditional Chinese medicinal plant with anti-inflammatory, immunosuppressive, contraceptive and antitumor activities. Its ...
DNA helicases open the duplex during DNA replication, repair and transcription. However, RNA polymerase II is the only member of its family with this requirement; RNA polymerases I and III and ...
Scientists at The Scripps Research Institute have determined the crystal structure of an enzyme called xeroderma pigmentosum group B (XPB) helicase, identifying several unexpected functions and ...
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