The scaffolding protein ankyrin G (AnkG; also known as ANK3) is restricted to the proximal part of axons, where it is required for the assembly of the axon initial segment (AIS) and for maintaining ...
June 21, 2012 — A neuronal protein may offer a potential target for immunization against Alzheimer's disease (AD), new research suggests. According to investigators from the University of Zurich, ...
A team led by Prof. WANG Chao and Prof. HUANG Chengdong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) revealed the molecular mechanism of ...
This is a preview. Log in through your library . Abstract High densities of ion channels at axon initial segments (AISs) and nodes of Ranvier are required for initiation, propagation, and modulation ...
Scientists have developed a new methodology that allows the study of CRISPR-mediated effects in cells while accurately ascertaining the exact DNA changes that caused them. This novel protocol is ...
As powerful as genome editing using CRISPR-Cas is, there are limitations to the technology. One of those has been the ability to determine genotypes of individual CRISPR-Cas transfected cells. Now, a ...
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