As reviewed in recent posts, bipolar I and bipolar II disorders are associated with substantial functional impairments and increased mortality. Depressive episodes associated with bipolar disorder do ...

Antidepressants are used to treat acute depression in patients with bipolar I disorder, but their effect as maintenance treatment after the remission of depression has not been well studied. We ...

Having bipolar disorder -- a serious mental illness that can cause both manic and depressed moods -- can make life more challenging. It also comes with a higher risk of dying early. Now, a study puts ...

Mood fluctuations are common during normal daily life as a result of either stressful or pleasant events. However, severe and persistent mood swings that result in psychological distress and ...

A study, published this month in the journal JAMA Psychiatry, sought to determine whether “a single psychedelic dose of psilocybin with psychotherapy demonstrate[s] evidence for efficacy and/or safety ...

Publication bias, especially the lack of publication of negative treatment studies, is known to be a major problem in the medical literature. In particular, it appears that the pharmaceutical industry ...

A potential new treatment for bipolar disorder (BP) that significantly shortens treatment time has emerged, following a randomized clinical trial using accelerated intermittent theta burst stimulation ...

Bipolar disorder is a mental health condition that can cause extreme changes in mood. It is also associated with various structural and functional changes in the brain. People with bipolar disorder ...