In one of the first research papers on an antidepressant, “The Treatment of Depressive States with G22355, Imipramine Hydrochloride,” the author noted that “in individuals who are predisposed” the ...

Bipolar disorder and alcohol problems seem to go hand-in-hand, leading to a widespread belief that drinking acts as a kind of 'self medication' to ease bipolar's life-altering symptoms of mania, ...

Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. Although bipolar disorder is a chronic ...

Bipolar disorder exists on a spectrum rather than as a single, uniform condition. This fundamental characteristic explains why two people with the same diagnosis can experience dramatically different ...

Subtle changes before a mood episode are often easiest to spot in hindsight. Here’s what to watch for. Managing a complex, brain-based mood disorder like bipolar requires self-awareness and a measure ...

Caplyta (lumateperone) was approved for the treatment of schizophrenia in 2019 and for depressive episodes linked to bipolar I or bipolar II disorder (bipolar depression) in 2021. Caplyta can be used ...

Schizophrenia and bipolar I disorder are two conditions that have many differences between them. A class of medicines called antipsychotics can be used to treat both conditions but may cause unwanted ...

The essential problem in assessing bipolar disorder with other mental disorders is the lack of a clear roadmap for an accurate differential diagnosis. As I have written before, nearly two-thirds of ...

Psoriasis is a chronic, inflammatory skin condition, but its effects go well beyond the skin. While it’s often recognized for its itchy, scaly patches, experts believe that the root causes of ...

Bipolar disorder can feel like a storm that erupts from nowhere, yet for decades the brain circuitry driving those brutal mood swings has remained frustratingly vague. Now, converging lines of ...