CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

Hydrocephalus, commonly referred to as "water on the brain," is a dangerous and potentially deadly condition that can harm the brain. For more than a century, physicians have believed that the buildup ...

Cerebrospinal fluid (CSF) leaks may be one of the mechanisms that link traumatic brain injury (TBI) with dementia, according to a recently published hypothesis in Alzheimer's & Dementia: Translational ...

Medically reviewed by Angela Ryan Lee, MD A CSF leak can cause symptoms such as headaches, nausea, and a runny nose. You can ...