Our cells move energy and matter to the places it is needed. But how do they do this in real time, and seen from the perspective of a single molecule? Scientists have successfully uncovered new basic ...

Parasitic wasps switch off the immune systems of fruit flies by draining calcium from the flies' blood cells, a finding that offers new insight into how pathogens break through a host's defenses.

Boston, MA - The improvement of intracellular calcium cycling, through overexpression of the sarcoplasmic reticulum CA 2+ ATPase pump (SERCA2a), reduces arrhythmias and restores contractile function ...

A key abnormality in heart failure is defective handling of calcium ions by cardiomyocytes. In the healthy heart, the action potential leads to an increase in the level of intracellular calcium (and ...

Although progress in conventional treatments is making steady and incremental gains to reduce mortality associated with heart failure (HF), there remains a need to explore potentially new therapeutic ...

We evaluated a family in which five siblings were affected by autosomal recessive sensorineural hearing loss. Despite the presumably shared cause of the disorder, there were clinically significant ...