I’ve been running WordPress on Nginx for a couple of years now with great success in our data center. We host roughly 100 installs on modestly provisioned VMs, some that handle 1 million+ page views ...
If you have an NGINX site that must allow users to upload files, try this configuration to help prevent possible Denial-of-Service attacks. Out of the box, NGINX sets a limit of 1MB for file uploads.
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