DNA origami suggests route to reusable, multifunctional biosensors Using an approach called DNA origami, scientists have developed a technique that could lead to cheaper, reusable biomarker sensors ...
A new microfluidic chip simplifies detecting and quantifying DNA by analyzing electrical impedance signals that vary based on DNA flowing across a biosensor inside the chip. The proof-of-concept ...
The sensor uses a DNA origami scaffold, which consists of two arms connected by a molecular “hinge.” Each arm is tagged with a fluorescent dye, and the distance between the tags is recorded by means ...
Fusobacterium nucleatum, a bacterium linked to colorectal cancer, possesses a specific gene called fadA that serves as an early diagnostic biomarker. The CRISPR/Cas12a system has demonstrated marked ...
The biosensor uses "capture probes" called aptamers, which are single strands of DNA that bind to virus proteins, flagging them. The team's big challenge was finding a way to get these aptamers to ...
A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.
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