Depression is a common mental health condition, with symptoms that can range from mild to severe. Around 16% of American adults have struggled with a type of depression at some point during their ...

In a recent study published in JAMA Network Open, researchers explored how structural and functional aspects of the brain, as seen through neuroimaging, differ between individuals with high exposure ...

As common as depression is—about one person in 10 experiences depression in any given year—it still eludes complete understanding. There does not seem to be a single cause; rather many factors ...

Treatment-resistant (refractory) depression has been a fertile topic for several decades (e.g., Freyhan, 1978; Nierenberg & Amsterdam, 1990; Voineskos, 2020). Unfortunately, as noted by Voineskos, ...

Depression affects millions of people worldwide, manifesting through various emotional, cognitive, and physical symptoms. While everyone experiences occasional sadness, clinical depression involves ...

Approximately 30% of people with major depression, have treatment-resistant depression, meaning it doesn’t respond to first and second-line antidepressants prescribed. While older people aren’t more ...