Two major studies have mapped how Down syndrome reshapes brain development before birth and traced the genetic evolution of a rare leukemia affecting children with the condition. UCLA researchers ...

A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

Scientists mapped human brain development in Down syndrome at a cellular level, discovering that stem cells "rush" to become ...

A research team led by scientists at Queen Mary University of London and University College London (UCL) has found new clues about how the brains of people with Down syndrome develop differently from ...

A missing brain molecule may be disrupting neural wiring in Down syndrome, according to new research. Replacing it in adult mice rewired brain circuits and improved brain flexibility, challenging the ...

Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule essential for the development and function of the nervous system, new research suggests. Restoring the ...