New research reveals that FGF21, a hormone under investigation for obesity and metabolic dysfunction-associated ...
NUDT21 regulates fibroblast senescence and is significantly decreased in aged and fibrotic lungs, impacting IPF progression. Alternative polyadenylation (APA) and NUDT21 downregulation enhance STAT3 ...
The Leo Foundation has awarded a $600,000 grant to Prof. Yossi Buganim’s lab at The Hebrew University of Jerusalem to support groundbreaking research on fibroblast dysfunction in aging skin. This ...
Fibroblast growth factor 21 (FGF21) analogs significantly improve fibrosis and resolve metabolic dysfunction-associated steatohepatitis (MASH) without progression, showing promise for non-cirrhotic ...
Fibroblast activation protein (FAP) is a serine protease, the expression of which increases with pathogenic fibroblasts in the fibrotic liver during metabolic dysfunction-associated steatohepatitis ...
L uis Garza, a physician-scientist at Johns Hopkins University School of Medicine for over a decade, noticed a common issue when treating people with limb amputations at his clinic. They often had ...
Heart failure (HF) is one of the leading causes of death and disability worldwide, affecting millions of people and placing an enormous burden on healthcare systems. The disease occurs when the heart ...
Older adults are much more likely to become seriously ill from flu or COVID because aging lung cells can drive excessive ...
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