Allogeneic hematopoietic stem-cell transplantation is the standard of care for Hurler syndrome (mucopolysaccharidosis type I, Hurler variant [MPSIH]). However, this treatment is only partially ...
Hematopoietic stem and progenitor cells (HSPCs) are capable of generating a large diversity of blood cells throughout the human lifespan. Although these cells have been extensively evaluated, there ...
Eltrombopag effect on the engraftment efficiency of human hematopoietic stem cells in a NOD/SCID xenotransplant model. Methods: Mice were treated with filgrastim (Neupogen) (FG) with or without ...
Editas Medicine Inc. has achieved in vivo preclinical proof of concept of hematopoietic stem and progenitor cell (HSPC) editing and fetal hemoglobin (HbF) induction in humanized mice engrafted with ...
New research shows that engineering epitopes on donor hematopoietic stem and progenitor cells (HSPCs) used in bone marrow transplants can give hematopoietic lineages selective resistance to monoclonal ...
A urine exosomal circRNA classifier for detection of high-grade prostate cancer at initial biopsy: A multicenter, retrospective study. Ability of cell-cycle progression score to predict risk for ...
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