Researchers at Nagoya University in Japan have identified two enzymes that are involved in macrophage polarization, one of the key factors affecting fibrosis. The group’s findings, reported in Cell ...

Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs. The MafB factor, a veritable ...

In a study that builds on earlier research that identified macrophages as essential to regeneration in the axolotl, a highly regenerative salamander, a scientist has identified the source of these ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...

Systemic lupus erythematosus (SLE) involves ongoing inflammation, tissue damage from immune complexes, and incomplete immune resolution. A key factor ...

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

Type 2 diabetes can turn immune cells that help with tissue repair and anti-inflammatory responses into triggers of chronic ...

A recent study has demonstrated the power of metabolic engineering in enhancing the antitumor activity of chimeric antigen ...

The understanding of how macrophages regulate their response to toxic particles via two independent pathways could uncover therapeutic opportunities to quell inflammation BIRMINGHAM, Ala. – Human ...