When cells are healthy, we don't expect them to suddenly change cell types. A skin cell on your hand won't naturally morph into a brain cell, and vice versa. That's thanks to epigenetic memory, which ...

For decades, dogma dictated that the immune system consisted of two separate branches. Cells of the innate system respond rapidly to molecular patterns shared by a broad array of pathogens. Meanwhile, ...

How does Alzheimer’s target specific brain cells? Researchers are building a multiscale model of the hippocampus to map neuronal loss and cognitive decline.

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, which are infection and tumor-fighting white blood cells, so that they have a ...

Microscopy images of antigen-inexperienced (‘naïve’) mouse CD8 T cells (green). A subset of these cells expresses Dapl1 protein (red), identifying a population committed to a memory stem-like lineage.

Psoriasis plaques have a stubborn habit of returning to the exact same patches of skin, even after months or years of apparent remission. For the millions of people living with this chronic ...

One of the most puzzling aspects of common chronic inflammatory skin diseases such as psoriasis is how they become chronic. What allows an ongoing condition to stay dormant for months or even years, ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...