To study the genetic causes of autism spectrum disorder, a Kobe University research team has created a bank of 63 mouse embryonic stem cell lines containing the mutations most strongly associated with ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Using the blastocyst complementation method, we produced rat embryonic stem (ES) cell-derived sperm in testicular hypoplasia mice and successfully generated rat offspring. This method can provide a ...

Rie Natsume and her collaborators have recently developed an innovative and cost-effective method for generating rats that inherit traits from embryonic stem (ES) cells. Unlike mouse ES cells, rat ES ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Red indicates mouse embryonic stem cells and green indicates mouse epiblast stem cells. The two cell types were co-cultured under GSK3α inhibition and maintained their distinct identities.