Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Every multicellular organism, from tiny worms to humans, elephants, and whales, needs a way for their cells to connect with ...

Sometimes, transporting electrons from one cell to another is a team effort. In electroactive bacteria, that team is a group of proteins that shepherds electrons forward, passing them along like a ...

Cataracts remain one of the world’s leading causes of vision loss, touching nearly every family at some point. Even when ...

A team at UT Southwestern Medical Center has identified a structural trick that lets viruses translate their genetic code inside human cells, even when that code is riddled with “bad” codons the host ...

In people destined to get Alzheimer's in their mid-40s, one protein can delay the onset of the disease by about 20 years.

In the evolutionary history of life, the ability of a cell to separate its inner world from the external environment was an ...