DNA repair protects genomic integrity and is vital for cell survival. Occasional failures in DNA repair can lead to multiple diseases, including cancer 1. UV light induces primarily cyclobutane ...
Targeting substrates to the proteasome is generally thought to depend on long polyubiquitin chains that form on the substrate. Recent work has led to the provocative proposal that some substrates may ...
Maintaining genomic integrity is the primary focus of DNA repair proteins. Though scientists have been able to elucidate many of the underlying mechanisms in complex repair pathways, how proteins can ...
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