T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...
A new form of CAR T kills leukemia, multiple myeloma, and sarcoma in mice, opening the door to a future off-the-shelf cancer ...
ATALANTA-1 data presented at ASH 2025 showed remarkable response rates and rapid manufacturing with an investigational autologous CAR T-cell therapy. In this interview, Michael Wang, MD, comments on ...
Pharmaceutical companies are shifting from the development of autologous cell therapies to allogeneic cell therapies.
As people age, their immune system function declines. T cell populations become smaller and can’t react to pathogens as quickly, making individuals more susceptible to a variety of infections. To try ...
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