Its true value depends not on the number of detected features but on the reliability of metabolite identification and pathway analysis. Despite well-established guidelines, annotation and definitive ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest ...

A proteomics data pipeline transforms raw mass spectrometry spectra into biologically interpretable protein-level measurements. This article explores the key steps in a proteomics data pipeline.

In what ways does chromatographic co-elution affect MS2 spectral quality, molecular networking, and the accuracy of ML models trained on MS2 data?

One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in Nature Communications, by a multidisciplinary team ...

Neurodegenerative disorders such as Alzheimer's disease (AD) are typically diagnosed after irreversible pathology has developed. Aging, the strongest risk factor, drives molecular changes that ...

One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others.

A global analysis of more than 2,300 seawater samples from more than 20 field studies around the globe indicates that ...

One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in ...

Researchers have reported detecting all five canonical nucleobases used in DNA and RNA in samples collected from the carbonaceous asteroid Ryugu, building on analyses enabled by Japan’s Hayabusa2 ...

With Raman microscopy, there's an additional layer of complexity: fluorescence. Particle fluorescence can overwhelm the Raman signal and make routine analysis more challenging. In comparison, IR ...