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Creatine is one of the most valuable supplements for both brain and body health. I typically take 5 grams twice a day of creatine monohydrate—powder form preferred for fewer additives. Recent research also shows that creatine may improve cognition in early-stage Alzheimer’s without serious side effects, making it a powerful tool to support mitochondrial function and metabolism. Consider adding creatine to your routine, especially if brain health is a priority. | David Perlmutter, M.D.
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I recently shared about berberine, a natural compound that supports fat metabolism and improves insulin sensitivity in a way similar to metformin. Since then, I’ve been asked whether eating barberries can provide a natural source of berberine. Barberries do contain berberine, usually around 5–7 percent, but the amount varies and you would need to eat a lot to reach an effective dosage. That’s why a high-quality berberine supplement is usually more reliable. Barberries and other nutrient-dense fr
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