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1:19
YouTube
Agios
Mutated Isocitrate Dehydrogenase Enzymes and Their Role in IDH Mutant Positive Cancers
Cellular metabolism is essential for all cells to carry out their normal functions. Isocitrate dehydrogenase enzymes (IDH1 and IDH2) help generate metabolites and provide energy for cells to carry out their normal functions. IDH enzymes catalyze the conversion of isocitrate to alpha-ketoglutarate (α-KG), an important metabolite that is ...
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