20 Slay the Spire Strategies to Win Your Next Run
20 Slay the Spire Strategies to Win Your Next Run
7.6K views6 months ago
wikiHowHunter Rising
This Run Completely Spun Out of Control… | Slay the Spire 2
1:14:13
This Run Completely Spun Out of Control… | Slay the Spire 2
277 views4 weeks ago
YouTubeNerdy Hickey
I Picked Every Power | Ascension 10 Defect Run | Slay the Spire 2
36:47
I Picked Every Power | Ascension 10 Defect Run | Slay the Spire 2
927 views3 weeks ago
YouTubevmService
Claw Run Of Your DREAMS!! (Hardest Ascension) | Slay The Spire 2 Defect
1:07:22
Claw Run Of Your DREAMS!! (Hardest Ascension) | Slay The Sp…
1.1K views1 month ago
YouTubeSloth
I Didn’t Expect This Defect Run to Go This Well… (Slay the Spire 2)
15:50
I Didn’t Expect This Defect Run to Go This Well… (Slay the Spire 2)
48 views2 weeks ago
YouTubeThe Kibosh0
First DEFECT Run Ever! Slay the Spire 2 - All for One and One For All! #slaythespire2 #deckbuilder
1:42:05
First DEFECT Run Ever! Slay the Spire 2 - All for One and One For …
1 month ago
YouTubeImpersonal Gaming
Slay The Spire 2 Defect Best Builds & Relics Guide (S Tier Strategies)
14:32
Slay The Spire 2 Defect Best Builds & Relics Guide (S Tier Strategies)
205 views1 month ago
YouTubeArcade Ranker
2:05
A Super Easy Infinite for the Defect | Slay the Spire 2
318 views2 months ago
YouTubeSuperCocoBro
47:43
A Simply Voltaic Defect Run
13.4K views1 month ago
YouTubeOlexa
1:05:25
I Got 8 Defragments… And It Broke The Game
943 views1 month ago
YouTubeNerdy Hickey
1:23:09
You Can't Lose If They Can't Hit You | Slay The Spire 2
26 views1 month ago
YouTubeNerdy Hickey
1:19:33
My First Defect Run!
263 views2 months ago
YouTubeOmni After Dark
40:43
Bad Decisions Somehow Win | Defect A6 | Slay The Spire 2
10 views1 month ago
YouTubeBad Deck Decisions
0:28
Defect Explained In Under 30 Seconds #slaythespire2 #slaythes…
30.9K views1 month ago
YouTubeNerdy Hickey
1:00:24
Okay dark orbs are SCARY! | Ascension 20 Defect Run | Slay th…
32.8K viewsAug 25, 2022
YouTubeJorbs
33:14
Slay The Spire - 9 CLAW Defect, Unbelievable Seed! | Ascension 15
310.4K viewsJun 1, 2018
YouTubejrm1ah
16:33
How to Play THE SILENT | Slay the Spire Guide and Tips
456.4K viewsDec 16, 2020
YouTubeInaBeta
21:43
BASIC STRATEGIES FOR DEFECT | SpireChats #39 | Slay the Spire
74.3K viewsJun 1, 2018
YouTubeJorbs
1:38:51
Highest Score!
31.8K viewsMay 4, 2022
YouTubeBaalorlord
52:30
Easy Turn 1 Kills!
54.5K viewsJul 10, 2024
YouTubeBaalorlord
1:15:39
1-in-1000 Defect Run!
64.5K views7 months ago
YouTubeBaalorlord
43:01
1HP CLUTCH ! Slay the Spire | Part 3
20 views5 months ago
YouTubeShoweird Gaming
1:15:41
1-in-a-Million Defect Run!
104.8K views8 months ago
YouTubeBaalorlord
2:02:06
Kill 100 A20 Hearts With Defect Only!
23.6K viewsMay 20, 2023
YouTubeBaalorlord
1:27:21
The Defect [Slay the Spire - Part 3]
17.2K viewsMar 1, 2025
YouTubeJohn Wolfe Gaming
1:38
Slay The Spire – How to unlock The Defect
42 views3 months ago
YouTubeHardReset.Info
2:39:31
Slay the Spire - Defect Runs - Learning the Character P2
49.2K viewsSep 22, 2018
YouTubeDay9TV
1:08:08
I ranked every Defect card in Slay The Spire
383.1K viewsFeb 17, 2021
YouTubeFrost Prime
2:38:37
How to Kill the Heart as Defect (Slay the Spire Guide)
232.8K viewsDec 10, 2022
YouTubeBaalorlord
2:16:51
How to Kill the Heart as Silent (Slay the Spire Guide)
256.9K viewsDec 4, 2022
YouTubeBaalorlord
See more videos
Static thumbnail place holder